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The specimens are samples of blood collected from infants by saturating marked areas of a filter paper card with blood obtained by skin puncture of the heel. In recognition of the role of Dr. Robert Guthrie in newborn screening, the specimen is now called the Guthrie spot. Each state has its own collection form on which some basic demographic information as well as the blood collection spots are recorded. Many factors determine the acceptability and quality of a specimen: the timing of collection, the provision of patient and specimen information, the collection of the blood specimen, and its subsequent handling. Problems with any of these may render a specimen invalid.
Collection of Screening Specimens
Timing of Specimen Collection
Collection of Blood Specimen
Specimen Handling
Invalid Specimens
Newborn Screening
March of Dimes Newborn Screening Recommendations
Newborn Screening: What Caregivers Need to Know, Online Course
Newborn Screening: What Caregivers Need to Know, Online Course
Clinical Issues and Considerations
Introduction and History
Collection of Screening Specimens
Disorders: Description and Sample Screening Methodology
Results and Follow-up
Parent Education
Professional Education
Frequently Asked Questions
Glossary of Newborn Screening Acronyms and Abbreviations
What Providers Can Do
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March of Dimes Information for Families
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Information specialists at the March of Dimes answer your questions by e-mail.
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© 2009 March of Dimes Foundation. All rights reserved. The March of Dimes is a not-for-profit organization recognized as tax-exempt under Internal Revenue Code section 501(c)(3). Our mission is to improve the health of babies by preventing birth defects, premature birth, and infant mortality.